Peter Benjamin Parker is the son of Richard and Mary Parker, who worked as NSA agents, and were killed on a mission involving an impersonator of the Red Skull. The infant Peter Parker is left in the care of his Uncle Ben and Aunt May Parker, who live in the Forest Hills neighborhood of Queens, New York. The aging couple love Peter, but he grows to be unpopular among his peers. Between an uncle who is too old to join him in physical activities and an aunt over-protective of the orphaned child, Peter gravitates to more non-physical hobbies such as photography and home chemistry, encouraged in these endevours by his guardians. Over time, he grows to be a lonely, timid but exceptionally bright teenager who shows more interest in his studies (especially science, which he has an affinity for that is nothing short of genius) than in any kind of social life. He is often the target of jokes by more popular students like Flash Thompson, the high school's star athlete.
Spider-Man's origin story is told in the first 12 pages of Amazing Fantasy #15. Peter Parker attends a science exhibition where he is bitten by a radioactive spider. The spider bite gives Peter an array of spider-like powers, including wall-crawling, superhuman strength, speed and agility, and an extra-sensory "spider-sense". Peter initially sets out to find fame and fortune, winning a match in a makeshift disguise against professional wrestler Crusher Hogan. He attempts to interest a television network in the idea of featuring him as a costumed hero (with the advantage that he can actually do the things his character can), and creates the Spider-Man name, costume, and web-shooters. After quickly becoming a minor celebrity, Peter appears on a television special, but afterward allows a thief to escape the TV station, asserting that it isn't his problem. He comes to regret his inaction when he finds out that the same burglar subsequently killed his Uncle Ben.
Peter blames himself for Uncle Ben's death. Art by Steve Ditko.Realizing that he could have prevented his uncle's death, the guilt-ridden Peter commits to a life of crimefighting and lifesaving, driven by his uncle's words, "With great power there must also come great responsibility" (the phrase is often shortened to: "With great power comes great responsibility"). This disarming mix of selfless obligation and self-recrimination brought about by his uncle's death arguably makes up Spider-Man's moral core.
In the earliest Spider-Man stories, Peter Parker attends Midtown High School. After his uncle's death, he and his aunt become desperate for money, so he gets a job as a photographer at the Daily Bugle selling photos to J. Jonah Jameson. Peter dates co-worker Betty Brant and clashes with his high school rival Flash Thompson (whose girlfriend, Liz Allen, he informally tutors). He encounters many of his most famous enemies for the first time during this period.
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